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AFIJI

Register aiming at evaluating the impact of genetics on occuring of coronary diseases in young patients and the pharmacogenetic of clopidogrel and its impact on the prognosis of patients having had angioplasty

En cours

La Grande Journée du Coeur (22 juin 2022)
Attention : plus que quelques places restantes !

Colloquium : Pathologies cardiaques de la femme (15 novembre 2022)
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objectif

Impact of genetics on occuring of coronary diseases in young patients and the pharmacogenetic of clopidogrel and its impact on the prognosis of patients having had angioplasty

date de réalisation

2009

nombre de patients

1200

nombre de centres participants

Monocentric (Cardiology institute, Pitié-Salpêtrière)

type de financement

Public (APHP)

Référence

-

Publications

  • Long-Term Evolution of Premature Coronary Artery Disease
    Jean-Philippe Collet, Michel Zeitouni, Niki Procopi, Jean-Sébastien Hulot, Johanne Silvain, Mathieu Kerneis, Daniel Thomas, Benoit Lattuca, Olivier Barthelemy, Yoan Lavie-Badie, Jean-Baptiste Esteve, Laurent Payot, Delphine Brugier, Izolina Lopes, Abdourahmane Diallo, Eric Vicaut, Gilles Montalescot, ACTION Study Group
    Publicated in Journal of the American College of Cardiology
  • CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics, and clinical efficacy in post-myocardial infarction patients
    Jean-Sébastien Hulot, Jean-Philippe Collet, Guillaume Cayla, Johanne Silvain, Frédérick Allanic, Anne Bellemain-Appaix, Stuart A Scott, Gilles Montalescot
    Publicated in Circulation : Cardiovascular Interventions
  • Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study
    Jean-Philippe Collet, Jean-Sébastien Hulot, Anna Pena, Eric Villard, Jean-Baptiste Esteve, Johanne Silvain, Laurent Payot, Delphine Brugier, Guillaume Cayla, Farzin Beygui, Gilbert Bensimon, Christian Funck-Brentano, Gilles Montalescot
    Publicated in The Lancet

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